Animal models of neurological and psychiatric disorders
Neuropharmatest’s Disease Models Program is designed to offer you many of the most commonly used and referenced efficacy models of neurological and psychiatric disorders. We offer several of the most popular rodent models, in which we have wide experience. The currently available models are listed below, but if you are interested in a particular model that it is not listed, please contact us.
Additionally, Neuropharmatest researchers are constantly working on the development of new models that will be able to reproduce more accurately different aspects of these disorders (see research).
Depression | Chronic stress
Chronic restraint stress
Chronic immobilization and acoustic stress
Chronic social stress (Aggression/Sensory-contact model)
Chronic unpredictable mild stress
Anxiety | Acute stress
Acute restraint stress
Acute immobilization and acoustic stress
Acute social stress
Predator sound/odor stress
MK-801 perinatal injection
Post-weaning social isolation rearing
“Double hit” schizophrenia model: This model combined neurological alterations during perinatal development (MK-801 injection at PND7) and modified environmental conditions (post-weaning social isolation rearing).
Understanding the pathophysiogenesis of temporal lobe epilepsy (TLE) largely rests on the use of models of status epilepticus (SE). At Neuropharmatest we are currently offering the following models.
Kainic acid model