Neuropharmatest performs analysis of neuronal structural plasticity in fixed tissue using Golgi staining or fluorescence/confocal microscopy: Dendritic/axonal remodeling and spine density.
We are also specialized in the analysis of neuronal structural remodeling in real time using mice strains with fluorescent excitatory and inhibitory interneurons. Confocal and multiphoton analysis of dendritic remodeling, spine density and perisomatic boutons.
Real-time analysis performed in:
Organotypic cultures of hippocampus and medial prefrontal cortex
Cortical neurons of living adult animals using a cranial window